Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade to nonylphenol through biochemical and photochemical processes. Because of the degradative processes to which APEOs are subject, they have recently been identified as restricted substances. There is significant evidence that NPEOs, and especially their degradation products, act as endocrine disruptors, which can have adverse effects on human’s health. As persistent pollutants with difficult degradation in nature, the problem of wastewater treatment and discharge gains considerable importance. Although these compounds can be determined by HPLC, LC/MS/MS represents the most effective and reliable way to analyze those compounds, as it provides more sensitivity and specificity. This application note reports a newly developed LC/MS/MS method for the determination of Alkylphenol Ethoxylates (APEO) and Alkylphenols (AP) in textiles using 爱游戏平台注册登录 UHPLC LX-50™ System coupled to the 爱游戏平台注册登录 QSight™ 210 Triple Quadrupole LC/MS/MS.